Horses that abort due to leptospirosis exposure tend to have very high mat titers.
Mat titers leptospirosis.
In the endemic regions there may be a substantial proportion of the population with elevated titres of mat.
For all 108 patients leptospirosis was diagnosed on the basis of a fourfold or greater increase in titer by mat seroconversion and all but 1 of 245 controls were mat negative titers 1 100.
What is the mat test for leptospirosis.
Laboratory studies can confirm the diagnosis and determine the extent of organ involvement.
The mat or microscopic agglutination test detects the presence of antibodies against leptospira in a dog s blood.
For the reading of mat titers it is highly recommended to use a darkfield microscope with a high contrast between the leptospires and the dark background.
In leptospirosis antibodies can be demonstrated in the serum by mat.
The mat is an excellent test but it.
As with other serology assays vaccination complicates the interpretation of titers.
The mat is the keystone for a correct diagnosis wolff 1954.
A severe form which includes jaundice kidney failure and bleeding is called weil disease.
Human leptospirosis is an acute febrile illness that presents with many manifestations and is found worldwide.
An interpretation is included in each mat report at no extra charge and additional consultation is also available.
Does the mat always work.
Detection of antibodies using the microscopic agglutination test mat has been the most common diagnostic method used for the diagnosis of canine leptospirosis 10 vaccination with commercially available leptospirosis vaccines will produce detectable mat titers 10 see algorithm 2 for more information on mat results.
Testing may include culture and or serology.
Results are expressed as the reciprocal of the highest dilution where agglutination is observed.
A series of cultures of different leptospires are incubated with serial dilutions of serum.
Sera are screened at a 1 100 dilution and those showing agglutination are then serially diluted further to determine a titer endpoint.
Lepto mat result interpretation the mat is a qualitative and quantitative test having high diagnostic specificity and relatively low sensitivity.
In equine abortion cases a mat titer of 1 6400 or higher is considered.
A single elevated mat titer in a patient with a compatible febrile illness and suspected exposure suggests acute leptospirosis.
Major disadvantages of microscopic agglutination test mat.
For all species of animals when chronic leptospirosis is suspected abortion anterior uveitis hepatitis and nephritis etc it is not necessary to collect a convalescent serum sample.
